Sigma-Aldrich Corporation has signed an exclusive global distribution agreement with IROA Technologies, LLC to distribute IROA’s Mass Spectrometry Metabolite Library of Standards™ (MSMLS). MSMLS is a collection of small molecules that span a broad range of primary metabolism. These are high purity (>95%) compounds supplied in an economical, ready-to-use format. The library of standards is most commonly used to provide retention times and spectra for key metabolic compounds, help optimise mass spectrometry analytical protocols and qualify and quantify mass spectrometry sensitivity and limit of detection.
Under the agreement, Sigma-Aldrich has worldwide rights to sell IROA Technologies’ Mass Spectrometry Metabolite Library of Standards and the corresponding software, MSMLSDiscovery™.
Learn more about Sigma-Aldrich's distribution of the Mass Spectrometry Metabolite Library of Standards, http://link.spectroscopyeurope.com/W5-09-005.




![Targeted proton transfer charge reduction (tPTCR) nano-DESI mass spectrometry imaging of liver tissue from orally dosed rat (Animal 3). a) optical image of a blood vessel within liver tissue. b) Composite ion image of charge-reduced haeme-bound α-globin (7+ and 6+ charge states; m/z 2259.9 and m/z 2636.3 respectively, red) and the charged-reduced [FABP+bezafibrate] complex (7+ and 6+ charge states; m/z 2097.5 and m/z 2446.9 respectively, blue). c) Ion image composed from charge-reduced haeme-bound α-globin (7+ and 6+ charge states) showing abundance in blood vessels. d) Ion image composed from charge-reduced [FABP+bezafibrate] complex (7+ and 6+ charge states) showing abundance in bulk tissue and absence in the blood vessel. Reproduced from https://doi.org/10.1002/ange.202202075 under a CC BY licence. Light and mass spectromert imaging of tissue samples](/sites/default/files/styles/thumbnail/public/news/MSI%20drug-protein%20complex-w.jpg?itok=CBNIjyYl)




