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Waters has introduced the Select Series Cyclic IMS, which integrates cyclic ion mobility (cIM) technology into a research-grade time-of-flight mass spectrometer. The Select Series Cyclic IMS replaces the traditional linear ion mobility region with a compact cyclic ion guide. Ions traverse around the ion guide and with every pass, greater ion mobility resolution is achieved. The cyclic device provides scalable, high-resolution ion mobility separations and introduces the unique ability to perform ion mobility/ion mobility and IMSn experiments, extending the benefits of routine ion mobility.