Photothermal Spectroscopy Corp. has announced the new mIRage-LS sub-500 nm IR multimodal microscope and spectroscopy system uniquely combining, simultaneous Raman and co-located fluorescence microscopy with sub-micron IR in a single platform. Additionally, new developments on their proprietary O-PTIR (Optical Photothermal IR Spectroscopy) technique have improved the IR spatial resolution to <500 nm for life science applications. The new integrated platform combines the benefits of fluorescence microscopy to support fast, easy targeting of molecular features of interest with sub-micron IR spectroscopy to characterise the molecular structure of bio-molecular features, including sub-cellular and tissue applications.